pentobarbital will lower the extent or result of guanfacine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Observe Carefully. Strong or reasonable CYP3A4 inducers drastically decrease guanfacine plasma concentrations and elimination 50 %-existence.
pentobarbital will boost the degree or outcome of ivosidenib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Steer clear of or Use Alternate Drug. Coadministration of ivosidenib with sturdy CYP3A4 inducers decreased ivosidenib plasma concentrations.
pentobarbital will decrease the level or impact of ripretinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will lessen the level or result of tofacitinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch. Lack of, or lowered response to tofacitinib may well arise when coadministered with powerful CYP3A4 inducers
pentobarbital will minimize the level or outcome of sunitinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.
pentobarbital will reduce the level or effect of cortisone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
pentobarbital will reduce the extent or result of fesoterodine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
Contraindicated (one)pentobarbital will lower the level or result of roflumilast by impacting hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will decrease the level or result of netupitant/palonosetron by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Steer clear of or Use Alternate Drug. Netupitant is especially metabolized by CYP3A4; avoid use in individuals who're chronically employing a robust get more info CYP3A4 inducer
pentobarbital will reduce the level or impact of ramelteon by impacting hepatic enzyme CYP2C9/10 metabolism. Insignificant/Importance Unidentified.
pentobarbital will minimize the level or outcome of theophylline by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.
pentobarbital will lower the extent or outcome of mavacamten by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.
pentobarbital will minimize the level or result of nelfinavir by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.
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